Application of the Ugi four-component reaction to the synthesis of ditopic bifunctional chelating agents

DOI: 10.1039/b907932g

Source and publish data:

Organic and Biomolecular Chemistry p. 4406 - 4414 (2009)

Update date:2022-07-30

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Authors:

Tei, Lorenzo

Gugliotta, Giuseppe

Avedano, Stefano

Giovenzana, Giovanni B.

Botta, Mauro

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Article abstract of DOI:10.1039/b907932g

The Ugi four-component reaction (Ugi 4CR) was exploited for the first time to obtain in a single synthetic step bifunctional ditopic chelators by using DOTA monoamide (DOTAMA) derivatives as amino and acid components. A number of ditopic systems in which

Full text of DOI:10.1039/b907932g

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