Tetrahedron Letters p. 6827 - 6830 (1988)
Update date:2022-08-06
Topics:
Kudzma, Linas V.
Spencer, H. Kenneth
Severnak, Sherry A.
Imines can be generated in situ from α-aminonitriles and efficiently trapped by a variety of lithiated heterocycles.This variation of the Bruylants reaction has proven to be a general method for the synthesis of α-heteroaryl secondary amines.
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