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153-18-4

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Product FOB Price Min.Order Supply Ability Supplier
High Quality 99% Rutin 153-18-4 / 250249-75-3 GMP Manufacturer
Cas No: 153-18-4
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Top quality Rutin with best price
Cas No: 153-18-4
USD $ 800.0-1000.0 / Kilogram 1 Kilogram 5000 Metric Ton/Day Kono Chem Co.,Ltd Contact Supplier
Rutin
Cas No: 153-18-4
USD $ 35.0-40.0 / Kilogram 25 Kilogram 300 Metric Ton/Year EXCELLENT HEALTH PRODUCTS CO.,LTD Contact Supplier
Pure Natural Plant Extract Powder Rutin 95% Manufacturer
Cas No: 153-18-4
USD $ 20.0-30.0 / Gram 10 Gram 100000 Kilogram/Month HANWAYS CHEMPHARM CO.,LIMITED Contact Supplier
GMP factory Supply NF11 Rutin
Cas No: 153-18-4
USD $ 18.0-18.0 / Kilogram 1 Kilogram 300 Kilogram/Month Greenutra Resource Inc Contact Supplier
Rutin
Cas No: 153-18-4
No Data No Data No Data Cartoon Ingredients Co., Ltd Contact Supplier
Rutin Manufacturer/High quality/Best price/In stock
Cas No: 153-18-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High purity Rutin with high quality cas:153-18-4
Cas No: 153-18-4
USD $ 22.0-50.0 / Kilogram 1 Kilogram 99999 Kilogram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Natural Health Supplements 99% troxerutin Rutin powder CAS 153-18-4
Cas No: 153-18-4
No Data 100 Kilogram 100 Metric Ton/Month Sinoway Industrial Co., Ltd. Contact Supplier
Factory supply Sophora Japonica extract / Sophora Japonica extract / Rutin 98% CAS NO.153-18-4
Cas No: 153-18-4
USD $ 1.0-3.0 / Kilogram 1 Kilogram 10 Kilogram/Day Hebei yanxi chemical co.,LTD. Contact Supplier

153-18-4 Usage

Uses

For nutritional product

Purification Methods

The vitamin crystallises from MeOH or water/EtOH, dry it in air, then dry it further for several hours at 110o or in high vacuum at 120o. It forms yellow crystals from EtOH/Me2CO/H2O (2:1:1). It has also been purified by passing (0.5g) through a Kieselgel column (30 x 5cm) with EtOAc/MeOH/H2O (100:20:15), and after 750mL have passed through, the yellow fraction of 250mL gives the glycoside (0.3g) on evaporation. [H.rhammer et al. Chem Ber 101 1183 1968, Marini-Bettòlo Gazz Chim Ital 80 631 1950, Beilstein 18/5 V 519.]

Uses

Found in many plants, especially the buckwheat plant. Identity with Ilixanthin. Capillary protectant. Rutin is colored brown by tobacco enzyme under experimental conditions.

Uses

antidiabetic, dipeptidyl peptidase–4 inhibitor

Chemical Properties

Pale-Yellow Crystalline Solid

Definition

ChEBI: A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.

Uses

rutin is described as helping to tighten and strengthen skin capillaries, and as such it could help prevent a couperose condition. It also demonstrates anti-oxidant properties. Rutin is a flavonoid found in rue leaves, buckwheat, and other plants.
InChI:InChI=1/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8?,15?,17-,18+,20-,21+,22?,23?,26+,27-/m0/s1

153-18-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name rutin

1.2 Other means of identification

Product number -
Other names Rutin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153-18-4 SDS

153-18-4Synthetic route

A

B

N,N,N',N'-tetramethyl-para-phenylenediamine
100-22-1

N,N,N',N'-tetramethyl-para-phenylenediamine

rutin radical

rutin radical

A

N,N,N',N'-tetramethyl-para-semiquinonediimine
100-22-1

N,N,N',N'-tetramethyl-para-semiquinonediimine

B

rutin
153-18-4

rutin

Conditions
ConditionsYield
at 20℃; Equilibrium constant; pH=13.5;
at 20℃; Rate constant; Equilibrium constant; pH=13.5;
potassium-compound of quercetin

potassium-compound of quercetin

Conditions
ConditionsYield
With α-acetobromorutinose in fluessigem NH3;

A

isoquercetin
482-35-9

isoquercetin

B

quercetol
117-39-5

quercetol

C

rutin
153-18-4

rutin

Conditions
ConditionsYield
With ammonium bicarbonate In acetic acid methyl ester; water at 45℃; for 0.75h; Purification / work up;
In acetic acid methyl ester; water at 45℃; for 0.5h; Purification / work up;
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-{6-deoxy-2-O-[(4-hydroxy-3,5-dimethoxyphenyl)carbonyl]-α-L-mannopyranosyl}-β-D-glucopyranoside

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-{6-deoxy-2-O-[(4-hydroxy-3,5-dimethoxyphenyl)carbonyl]-α-L-mannopyranosyl}-β-D-glucopyranoside

rutin
153-18-4

rutin

Conditions
ConditionsYield
With sodium methylate In methanol at 20℃; for 1h;
isoquercetin
482-35-9

isoquercetin

Conditions
ConditionsYield
With Aspergillus niger crude enzyme extract In methanol at 60℃; for 4h; pH=6; aq. piperazine-HCl buffer; Enzymatic reaction;99%
With hesperidinase In aq. buffer at 40℃; for 0.666667h; pH=9; Activation energy; Temperature; Concentration; Ionic liquid; Enzymatic reaction;98.6%
With hesperidinase from Aspergillus niger; water In aq. buffer at 40℃; for 0.666667h; pH=9; Temperature; Flow reactor; Enzymatic reaction;98.6%
rutin
153-18-4

rutin

rutin 2'',2''',3',3'',3''',4',4'',4''',5, 7-O-decasulfate

rutin 2'',2''',3',3'',3''',4',4'',4''',5, 7-O-decasulfate

Conditions
ConditionsYield
Stage #1: rutin With triethylamine sulfurtrioxide In N,N-dimethyl acetamide at 20 - 100℃; for 0.5h; Microwave irradiation;
Stage #2: With triethylamine In N,N-dimethyl acetamide; acetone at 4℃; for 24h;
Stage #3: With sodium acetate In water
99%
Conditions
ConditionsYield
With hydrogenchloride; methanol for 3h; Heating;96%
With water at 100℃; Kinetics; Ionic liquid;90%
With sulfuric acid; water at 20℃; for 0.166667h;89%
rutin

rutin

troxerutin
7085-55-4

troxerutin

Conditions
ConditionsYield
With chitosan In methanol at 75℃; for 3h; Concentration; Temperature; Autoclave;96%
With natural polymer sodium alginate In methanol at 70℃; for 4h; Temperature; Autoclave;87.6%
Stage #1: oxirane; rutin With sodium hydroxide In water at 75℃; for 6h;
Stage #2: With hydrogenchloride In water pH=4;
rutin
153-18-4

rutin

isoquercitrin

isoquercitrin

Conditions
ConditionsYield
With α-L-rhamnosidase from Aspergillus niger JMU-TS528 at 60℃; for 1h; pH=3 - 5; Kinetics; Catalytic behavior; pH-value; Temperature; Concentration; Enzymatic reaction;95.1%
succinic acid anhydride
108-30-5

succinic acid anhydride

rutin
153-18-4

rutin

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{{2,3,4-tris-O-(3-carboxy-1-oxopropyl)-6-O-[2,3,4-tris-O-(3-carboxy-1-oxopropyl)-6-deoxy-α-L-mannopyranosyl]-β-D-glucopyranosyl}oxy}-4H-1-benzopyran-4-one

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{{2,3,4-tris-O-(3-carboxy-1-oxopropyl)-6-O-[2,3,4-tris-O-(3-carboxy-1-oxopropyl)-6-deoxy-α-L-mannopyranosyl]-β-D-glucopyranosyl}oxy}-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With pyridine; dmap at 70℃; for 24h; Esterification;95%
rutin
153-18-4

rutin

2-bromoethanol
540-51-2

2-bromoethanol

troxerutin
7085-55-4

troxerutin

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80 - 85℃;94.9%
benzyl bromide
100-39-0

benzyl bromide

rutin
153-18-4

rutin

2-(3,4-bis(benzyloxy)phenyl)-7-(benzyloxy)-3,5-dihydroxy-4H-chromen-4-one
183067-65-4

2-(3,4-bis(benzyloxy)phenyl)-7-(benzyloxy)-3,5-dihydroxy-4H-chromen-4-one

Conditions
ConditionsYield
Stage #1: benzyl bromide; rutin With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 3h; Inert atmosphere;
Stage #2: With hydrogenchloride In ethanol; water at 70℃; for 2h; regioselective reaction;
92%
Stage #1: rutin With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 20℃; for 16h; Cooling with ice;
81.2%
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 60h; Inert atmosphere;80%
Stage #1: benzyl bromide; rutin With potassium carbonate In N,N-dimethyl-formamide at 20 - 50℃; for 0.25h;
Stage #2: With hydrogenchloride In ethanol; water; N,N-dimethyl-formamide at 78℃; for 2h;
43%
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 10 h / 20 °C
2: hydrogenchloride / ethanol; water / 2 h / Reflux
View Scheme
rutin
153-18-4

rutin

methyl iodide
74-88-4

methyl iodide

2-(3,4-dimethoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one
6068-80-0

2-(3,4-dimethoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one

Conditions
ConditionsYield
Stage #1: rutin; methyl iodide With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 3h; Inert atmosphere;
Stage #2: With hydrogenchloride In ethanol; water at 70℃; for 2h;
91%
oxirane
75-21-8

oxirane

rutin
153-18-4

rutin

7-mono-O-(β-hydroxyetyl)rutoside
23869-24-1

7-mono-O-(β-hydroxyetyl)rutoside

Conditions
ConditionsYield
Stage #1: rutin With sodium tetraborate decahydrate In water at 40 - 45℃;
Stage #2: oxirane In water at 40 - 45℃; for 6h; Reagent/catalyst;
90.1%
Stage #1: rutin With sodium tetraborate decahydrate In water at 40 - 45℃;
Stage #2: oxirane In water at 40 - 45℃; for 6h; Reagent/catalyst;
84.8%
acetic anhydride
108-24-7

acetic anhydride

rutin
153-18-4

rutin

2'',2''',3',3'',3''',4',4'',4''',5,7-deca-O-acetylrutin
2328-13-4

2'',2''',3',3'',3''',4',4'',4''',5,7-deca-O-acetylrutin

Conditions
ConditionsYield
With pyridine; dmap at 20℃; for 12h; Inert atmosphere;90%
With pyridine; dmap at 20℃; for 12h; Inert atmosphere;90%
With dmap In pyridine at 20℃; for 18h;84%
rutin
153-18-4

rutin

2-chloro-ethanol
107-07-3

2-chloro-ethanol

troxerutin
7085-55-4

troxerutin

Conditions
ConditionsYield
With potassium hydroxide at 68℃; for 24h; Temperature; Inert atmosphere;90%
With potassium carbonate In N,N-dimethyl-formamide for 0.133333h; Heating;
rutin
153-18-4

rutin

C22H11F3N2O11
1333241-01-2

C22H11F3N2O11

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80 - 90℃; for 15h;90%
propionyl chloride
79-03-8

propionyl chloride

rutin
153-18-4

rutin

C57H70O26

C57H70O26

Conditions
ConditionsYield
With dmap In dichloromethane at 0 - 20℃; for 14h;73%
(2E)-3-phenyl-2-propen-1-ol
4407-36-7

(2E)-3-phenyl-2-propen-1-ol

rutin
153-18-4

rutin

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol
85026-55-7

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol

Conditions
ConditionsYield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger In aq. phosphate buffer; dimethyl sulfoxide at 35℃; for 8h; pH=5; Enzymatic reaction;70%
rutin
153-18-4

rutin

C22H32O12

C22H32O12

Conditions
ConditionsYield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger In aq. phosphate buffer; dimethyl sulfoxide at 35℃; for 8h; pH=5; Enzymatic reaction; regioselective reaction;70%
ortho-toluoyl chloride
933-88-0

ortho-toluoyl chloride

rutin
153-18-4

rutin

C55H40O12

C55H40O12

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 55℃; for 5h;68.1%
(E)-4-(3-hydroxyprop-1-enyl)phenol
20649-40-5

(E)-4-(3-hydroxyprop-1-enyl)phenol

rutin
153-18-4

rutin

4-hydroxycinnamyl alcohol 9-O-β-D-glucopyranoside
132294-76-9

4-hydroxycinnamyl alcohol 9-O-β-D-glucopyranoside

Conditions
ConditionsYield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger In aq. phosphate buffer; dimethyl sulfoxide at 35℃; for 8h; pH=5; Enzymatic reaction; regioselective reaction;68%
p-ethylbenzoyl chloride
16331-45-6

p-ethylbenzoyl chloride

rutin
153-18-4

rutin

C60H50O12

C60H50O12

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 62℃; for 4h;63.4%
Conditions
ConditionsYield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger K2 in Pichia pastoris In aq. phosphate buffer; dimethyl sulfoxide at 35 - 100℃; for 24h; pH=5; Enzymatic reaction;A 63%
B n/a
With rhamnodiastase Reactivity; Enzymatic reaction;
With rutinosidase In water Enzymatic reaction;
tin(II) chloride dihdyrate
10025-69-1

tin(II) chloride dihdyrate

rutin
153-18-4

rutin

C54H56O32Sn

C54H56O32Sn

Conditions
ConditionsYield
Stage #1: tin(II) chloride dihdyrate; rutin In methanol at 20℃; for 0.5h;
Stage #2: With sodium methylate In methanol for 6h; pH=9; Reflux;
62%
4-chloro-benzoyl chloride
122-01-0

4-chloro-benzoyl chloride

rutin
153-18-4

rutin

C50H25Cl5O12

C50H25Cl5O12

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 74℃; for 4h;61.3%
3,5-dimethylbenzoyl chloride
6613-44-1

3,5-dimethylbenzoyl chloride

rutin
153-18-4

rutin

C60H50O12

C60H50O12

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 58℃; for 4h;61.1%
benzyl bromide
100-39-0

benzyl bromide

rutin
153-18-4

rutin

C48H48O16

C48H48O16

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 4h;61%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 4h;61%
Stage #1: rutin With potassium carbonate In N,N-dimethyl-formamide for 0.5h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 60℃; for 3h;
phenylacetyl chloride
103-80-0

phenylacetyl chloride

rutin
153-18-4

rutin

C55H40O12

C55H40O12

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 57℃; for 4h;60.5%
Conditions
ConditionsYield
With hydrogenchloride; amalgamated zinc In methanol for 0.166667h;60%

A

B

quercetol
117-39-5

quercetol

Conditions
ConditionsYield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger In dimethyl sulfoxide at 35℃; for 8h; pH=5; Enzymatic reaction;A 60%
B n/a
o-chlorobenzoyl chloride
609-65-4

o-chlorobenzoyl chloride

rutin
153-18-4

rutin

C50H25Cl5O12

C50H25Cl5O12

Conditions
ConditionsYield
With piperidine In N,N-dimethyl-formamide at 75℃; for 4h;58.8%
acetic anhydride
108-24-7

acetic anhydride

rutin
153-18-4

rutin

3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one
1064-06-8

3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one

Conditions
ConditionsYield
With sulfuric acid at 65℃; for 6h;58.2%
(E)-p-methoxy-cinnamyl alcohol
53484-50-7

(E)-p-methoxy-cinnamyl alcohol

rutin
153-18-4

rutin

4-methoxy-cinnamyl O-β-D-glucopyranoside
143729-77-5

4-methoxy-cinnamyl O-β-D-glucopyranoside

Conditions
ConditionsYield
With α-L-rhamnosyl-β-D-glucosidase from Aspergillus niger In aq. phosphate buffer; dimethyl sulfoxide at 35℃; for 8h; pH=5; Enzymatic reaction;58%

153-18-4Downstream Products

153-18-4Related news

The light‐induced transcription factor FtMYB116 promotes accumulation of Rutin (cas 153-18-4) in Fagopyrum tataricum09/30/2019

Tartary buckwheat (Fagopyrum tataricum) not only provides a supplement to primary grain crops in China but also has high medicinal value, by virtue of its rich content of flavonoids possessing antioxidant, anti‐inflammatory, and anticancer properties. Light is an important environmental factor ...detailed

Purified Rutin (cas 153-18-4) and Rutin (cas 153-18-4)‐rich asparagus attenuates disease severity and tissue damage following dextran sodium sulfate‐induced colitis09/29/2019

Scope This study investigated the effects of cooked whole asparagus (ASP) versus its equivalent level of purified flavonoid glycoside, rutin (RUT), on dextran sodium sulfate (DSS)‐induced colitis and subsequent colitis recovery in mice.Methods and results C57BL/6 male mice were fed an AIN‐93G ...detailed

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