
Tetrahedron p. 6055 - 6064 (1988)
Update date:2022-08-03
Topics:
Loubinoux, Bernard
Tabbache, Samir
Gerardin, Philippe
Miazimbakana, Joseph
Phenols are protected by the azidomethylene group in basic, nucleophilic, oxidative, weakly reductive and weakly acidic media.This group is obtained by the reaction of sodium azide with aryloxymethyl chlorides.Its utility lies in the ease with which it can be removed under very mild conditions which allows the synthesis of very unstable phenolic compounds.
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