The first example of the cascade assembly of a spirocyclopropane structure: direct transformation of benzylidenemalononitriles and N,N′-dialkylbarbituric acids into substituted 2-aryl-4,6,8-trioxo-5,7-diazaspiro[2.5]octane-1,1-dicarbonitriles

DOI: 10.1016/j.tetlet.2009.11.065

Source and publish data:

Tetrahedron Letters p. 428 - 431 (2010)

Update date:2022-08-02

Topics:

Authors:

Elinson, Michail N.

Vereshchagin, Anatolii N.

Stepanov, Nikita O.

Zaimovskaya, Tatiana A.

Merkulova, Valentina M.

Nikishin, Gennady I.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.tetlet.2009.11.065

The direct formation of substituted 2-aryl-4,6,8-trioxo-5,7-diazaspiro[2.5]octane-1,1-dicarbonitriles in 75-95% yields from benzylidenemalononitriles and N,N′-dialkylbarbituric acids is described.

Full text of DOI:10.1016/j.tetlet.2009.11.065

Products guided by the article

Product name:5,7-diethyl-2-(4-methylphenyl)-4,6,8-trioxo-5,7-diazaspiro[2.5]octane-1,1-dicarbonitrile

Cas No:1207614-78-5

R&D Labs maybe for 1207614-78-5

Jiangyin Tenghua Import&Export Co.,Ltd.

Contact:+86-510-86263875

Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
Shaanxi Lighte Optoelectronics Material Co., Ltd.

Contact:+86-29-88320728-622/619/620

Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.
Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road

Relevant to this article

Doi:10.1007/BF01427017
()
Z-Selective Addition of Diaryl Phosphine Oxides to Alkynes via Photoredox Catalysis

Doi:10.1021/acscatal.8b02617
(2018)
Copper-catalyzed enantioselective 1,4-conjugate addition of dialkylzinc reagents to α,β- and α,β,γ,δ-unsaturated ketones

Doi:10.1016/j.tet.2019.05.029
(2019)
Azido, cyanato, and thiocyanato coordination induced distortions in pentacoordinated [Co^IIA(bip)]₂ (A = NCS^-, N₃^-, or NCO^-) Complexes

Doi:10.1002/ejic.200900577
(2009)
Novel azo disperse dyes derived from N-benzyl-N-ethyl-aniline: Synthesis, solvatochromic and optical properties

Doi:10.1016/j.molliq.2009.11.010
(2010)
A 2,6-bis(phenylamino)pyridinato titanium catalyst for the highly regioselective hydroaminoalkylation of styrenes and 1,3-butadienes

Doi:10.1002/anie.201403203
(2014)

Article Doi