General Synthesis of 2'(3')-O-Aminoacyl Oligoribonucleotides. The Protection of the Guanine Moiety

DOI: 10.1021/jo00274a041

Source and publish data:

Journal of Organic Chemistry p. 3189 - 3195 (1989)

Update date:2022-08-05

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Authors:

Hagen, Michael D.

Chladek, Stanislav

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Article abstract of DOI:10.1021/jo00274a041

The chemical synthesis of 2'(3')-O-aminoacyl oligoribonucleotides requires the development of a specific blocking scheme for all nucleoside components.Herein, we describe the synthesis of guanosine synthons protected at the O⁶-position with the

Full text of DOI:10.1021/jo00274a041

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