General Synthesis of 2'(3')-O-Aminoacyl Oligoribonucleotides. The Protection of the Guanine Moiety

Article abstract of DOI:10.1021/jo00274a041

The chemical synthesis of 2'(3')-O-aminoacyl oligoribonucleotides requires the development of a specific blocking scheme for all nucleoside components.Herein, we describe the synthesis of guanosine synthons protected at the O⁶-position with the