
European Journal of Organic Chemistry p. 3584 - 3591 (2016)
Update date:2022-09-26
Topics:
Durán-Pe?a, María Jesús
Botubol-Ares, José Manuel
Hanson, James R.
Hernández-Galán, Rosario
Collado, Isidro G.
A method has been developed for the conversion of primary, secondary, and tertiary alcohols, and phenol, into the corresponding esters at room temperature. The method uses a titanium(III) species generated from a substoichiometric amount of titanocene dichloride together with manganese(0) as a reductant, as well as methylene diiodide. It involves a transesterification from an ethyl ester, or a reaction with an acyl chloride. A radical mechanism is proposed for these transformations.
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