An Efficient Synthesis of 4,4-Disubstituted 5,6-Dihydro-3(4H)-pyridinone 1-Oxides by Thermal Cyclisation of Unsaturated 1,2-Hydroxyiminoketones

Article abstract of DOI:10.1055/s-1988-27784

3,3-Disubstituted 1,2-hydroxyiminoketones 6 with the hydroxyimino group distal and δ,ε to an olefinic bond undergo thermal cyclisation to produce high yields of 4,4-disubstituted 5,6-dihydro-3(4H)-pyridinone 1-oxides 7.