Synthesis and Pharmacological Evaluation of CNS Activities of Triazolo-, Imidazolo-, and Pyridobenzodiazepines. 10-Piperazinyl-4H-1,2,3-triazolobenzodiazepines with Neuroleptic Activity

Article abstract of DOI:10.1021/jm00130a025

The synthesis of <1,2,3>triazolo<4,5-b><1,5>-, imidazolo<4,5-b><1,5>-, and pyrido<2,3-b><1,5>benzodiazepines is described.The antidopaminergic and anticholinergic activities of the compounds have been examined by the respective in vitro <³H>spi