Chemistry of Heterocyclic Compounds p. 47 - 50 (1989)
Update date:2022-07-29
Topics:
Shachkus, A. A.
Degutis, Yu. A.
Mikul'skis, P. P.
Derivatives of 1,3-dihydrospiro<2H-indole-2,2'-pyrrolidine> were synthesized by the reaction of 2-methylene-2,3-dihydro-1H-indoles with α-iodoacetamide.Treatment of the products with alkyl iodides in the presence of potassium hydroxide gave 1'-substituted spiroindole-2,2'-pyrrolidines.The 1,3-dihydrospiro<2H-indole-2,2'-pyrrolidines> were converted by the action of perchloric acid into 2-(2-carbamoylethyl)-3H-indolium perchlorates.
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