Journal of Organic Chemistry p. 5094 - 5100 (1989)
Update date:2022-08-04
Topics:
Makosza, M.
Owczarczyk, Z.
Trichloro- and tribromomethyl carbanions generated by deprotonation of haloforms with potassium tert-butoxide in a THF-DMF mixture at ca. -70 deg C react with a variety of carbocyclic and heterocyclic nitroarenes according to the vicarious nucleophilic substitution scheme.The reaction provides an efficient and convenient way for the direct introduction of dihalomethyl substituents ortho and para to the nitro group, which in turn can be hydrolyzed to produce nitroaryl aldehydes.
View MoreLanzhou huibang biological chemical technology Co., LTD
Contact:0931-7843964
Address:NO.2011,Yannan Road,Chengguan,
Shanghai united Scientific Co.,Ltd.
Contact:+86-21-53535353
Address:28F No.900 huaihai Road Shanghai China
Nanjing Habo Medical Technology Co., Ltd.
Contact:025－85769882
Address:No.108. Ganjiabian east. Qixia District .Nanjing
Chengdu Biopurify Phytochemicals Ltd.
website:http://www.phytopurify.com
Contact:+86-28-82633397
Address:2F,No.11 Building,No.388 Rongtaidadao CNSTP,Wenjiang Zone,Chengdu,Sichuan, China
Shanghai Dianyang Industry Co.,ltd
Contact:+86 21 6492 4669
Address:Chejing RD, Songjiang District, Shanghai, China
Doi:10.1016/j.bmcl.2009.12.030
(2010)Doi:10.1016/j.jinorgbio.2019.110781
(2019)Doi:10.1039/c5ra04729c
(2015)Doi:10.1021/ol100446p
(2010)Doi:10.1021/ja100517v
(2010)Doi:10.1016/S0040-4020(01)89795-7
(1988)
