Divergent total synthesis of crassalactones B and C and evaluation of their antiproliferative activity

DOI: 10.1016/j.tet.2015.05.040

Source and publish data:

Tetrahedron p. 4581 - 4589 (2015)

Update date:2022-08-05

Topics:

Authors:

Benedekovi?, Goran

Kova?evi?, Ivana

Popsavin, Mirjana

Francuz, Jovana

Koji?, Vesna

Bogdanovi?, Gordana

Popsavin, Velimir

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Article abstract of DOI:10.1016/j.tet.2015.05.040

A divergent total synthesis of cytotoxic natural products (+)-crassalactones B (2) and C (3) has been achieved by utilizing diacetone d-glucose (4) as a chiral precursor. The key steps of the synthesis of both targets 2 and 3 were a stereo-selective addit

Full text of DOI:10.1016/j.tet.2015.05.040

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Product name:3,6-anhydro-7-O-(tert-butyldiphenylsilyl)-5-O-cinnamoyl-2-deoxy-7-C-phenyl-D-glycero-D-ido-heptono-1,4-lactone

Cas No:1233484-19-9

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