Journal of the Chemical Society. Perkin transactions I p. 2849 - 2858 (1994)
Update date:2022-08-05
Topics:
Nakashima, Hideki
Hirata, Norihiko
Iwamura, Takeru
Yamagiwa, Yoshiro
Kamikawa, Tadao
(2S,3S,4R)-2-<(2'R)-2-Benzoyloxydocosanoylamino>-16-methylheptadecane-1,3,4-triol 3,4-dibenzoate 32, apertially protected ceramide part of a cerebroside from the marine sponge Halichondria japonica, has been synthesized from L-ascorbic acid, and its absolute stereochemistry has been determined.The key steps in the synthesis include the regioselective ring opening of chiral epoxide 5 with a 2-alkyl-2-lithio-1,3-dithiane and the introduction of a hydroxymethylene synthon using Dondoni's protocol to assemble C(1) and C(2) functionality.
View MoreChangzhou Sunlight Pharmaceutical Co., Ltd.
Contact:+86-519-83131668;83139028;83138042;83137041
Address:JiuliStreet, Benniu Town Changzhou City, Jiangsu Province
Shandong Bolode Bio-Technology Co., LTD
Contact:+86-0531-58966870
Address:136 Jingyi Road,Huaiyin District,Jinan,Shandong,China
Tai zhou world Pharm & Chem Co., Ltd
Contact:+86-576-85301198
Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Wuhan Silworld Chemical Co.,Ltd
website:http://www.silworldchemical.com
Contact:+86-27-85613400
Address:No.198 jiangjun Road, Wuhan,China 430033
Hangzhou jls Flame Retardants Chemical Co.,Ltd
Contact:+86-571-87250387/87250386
Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
Doi:10.1021/jm00170a017
(1990)Doi:10.1021/ja105121z
(2010)Doi:10.1021/ja00158a079
(1990)Doi:10.1016/0223-5234(89)90111-6
(1989)Doi:10.1016/j.bmc.2010.06.071
(2010)Doi:10.1039/a808293f
(1999)
