Diastereoselective synthesis of cis-fused pyrano[4,5-c]pyrrole derivatives via microwave-accelerated intramolecular Knoevenagal hetero Diels-Alder reaction

Article abstract of DOI:10.1016/j.tetasy.2010.10.025

The synthesis of enantiomerically pure pyrano[4,5-c]pyrroles has been accomplished by the intramolecular hetero Diels-Alder reaction of enantiomerically pure N-allyltetheredalkenyl aldehydes with various 1,3-diones. The reaction led to the formation of ci