New Synthesis of the 6H-Pyridocarbazoles Ellipticine and Olivacine via Cycloaddition of 2-Phenylsulfonyl 1,3-Dienes to Indoles

DOI: 10.1021/jo00302a013

Source and publish data:

Journal of Organic Chemistry p. 4528 - 4531 (1990)

Update date:2022-08-04

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Authors:

Baeckvall, Jan-E.

Plobeck, Niklas A.

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Article abstract of DOI:10.1021/jo00302a013

An efficient synthesis of the antitumor alkaloids ellipticine and olivacine, starting from indole, was developed.The cycloaddition of 3-(phenylsulfonyl)-2,4-hexadiene or 2-(phenylsulfonyl)-1,3-pentadiene to the magnesium salt of indole was followed by C-C

Full text of DOI:10.1021/jo00302a013

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