Tetrahedron Letters p. 7219 - 7222 (1990)
Update date:2022-07-29
Topics:
Janssen
Klunder
Zwanenburg
The enzymatic resolution of some norbornene esters, -carboxylic acids and -methanols was evaluated. Good results were obtained for the Porcine Pancreatic Lipase (PPL) catalyzed transesterification of norbornene methanols 12 and 13 in methyl acetate. A formal kinetic resolution of endo-norbornene lactone 7 could be achieved through the PPL-catalyzed transesterification of iodolactone 15 in methyl acetate. Both enantiomers of lactone 7 were obtained enantiomerically pure in good overall yields.
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Doi:10.1080/24701556.2020.1852250
(2021)Doi:10.1002/ejic.201000959
(2011)Doi:10.1016/0022-328X(90)80002-H
(1990)Doi:10.1039/c39900000428
(1990)Doi:10.1055/s-0030-1258351
(2011)Doi:10.1021/jo960453f
(1996)
