EFFICIENT SYNTHESIS OF (+)-NOJIRIMYCIN AND (+)-1-DEOXYNOJIRIMYCIN

DOI: 10.1016/0040-4039(90)80078-Z

Source and publish data:

Tetrahedron Letters p. 2085 - 2088 (1990)

Update date:2022-08-03

Topics:

Authors:

Anzeveno, Peter B.

Creemer, Laura J.

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Article abstract of DOI:10.1016/0040-4039(90)80078-Z

(+)-Nojirimycin (1a) and (+)-1-deoxynojirimycin (2) have been prepared from 1,2-O-isopropylidene-α-D-glucofuranurono-6,3-lactone (3) by a route involving stereoselective reductive amination of 5-hydroxy-1,2-O-isopropylidene-α-D-xylo-hexofuranurono-6,3-lactone (5a).

Full text of DOI:10.1016/0040-4039(90)80078-Z

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