European Journal of Medicinal Chemistry p. 369 - 374 (1990)
Update date:2022-07-30
Topics:
Aranda
Beaucourt
Ponchant
Isambert
Henry
The synthesis of a photosensitive iodinated derivative of tetrabenazine, which should be able to lead to the identification of the vesicular catecholamine transporter of adrenal medulla by photoaffinity, is described in detail. The biological activity of this iodinated ligand was found to be significantly lower than that of non iodinated ligands.
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