7-Deaza-2-phenyladenines: Structure-activity relationship of potent A1 selective adenosine receptor antagonists

DOI: 10.1021/jm00172a023

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Journal of Medicinal Chemistry p. 2822 - 2828 (1990)

Update date:2022-09-26

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Authors:

Muller Muller

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Dalky Dalky

Rothenhausler

Eger Eger

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Article abstract of DOI:10.1021/jm00172a023

A series of derivatives of 7-deazapurines with varying substituents in the 2-, 6-, and 9-position was synthesized in an attempt to improve the adenosine receptor affinity and A₁ and A₂ selectivity. The adenosine receptor affinities w

Full text of DOI:10.1021/jm00172a023

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