Potent inhibitors of hepatitis C core dimerization as new leads for anti-hepatitis C agents

DOI: 10.1016/j.bmcl.2011.03.014

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2198 - 2202 (2011)

Update date:2022-08-04

Topics:

Authors:

Ni, Feng

Kota, Smitha

Takahashi, Virginia

Strosberg, A. Donny

Snyder, John K.

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Article abstract of DOI:10.1016/j.bmcl.2011.03.014

New indoline alkaloid-type compounds which inhibit HCV production by infected hepatoma cells have been identified. These compounds, dimeric-type compounds of previously known inhibitors, display double digit nanomolar IC ₅₀ and EC₅₀

Full text of DOI:10.1016/j.bmcl.2011.03.014

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