An efficient synthesis of 13(S)-hydroxy-9Z,11E-octadecadienoic (coriolic) acid

DOI: 10.1016/0040-4039(90)80129-A

Source and publish data:

Tetrahedron Letters p. 2577 - 2580 (1990)

Update date:2022-09-26

Topics: Synthesis Yield Organic synthesis Hydroxy Efficient Synthesis Experimental

Authors:

Bloch Bloch

Perfetti

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Article abstract of DOI:10.1016/0040-4039(90)80129-A

An efficient and highly selective total synthesis of 13(S)-hydroxy-9Z,11E octadecadienoic (coriolic) acid is described, starting from an optically active lactol easily available though an enantioselective enzymatic hydrolysis.

Full text of DOI:10.1016/0040-4039(90)80129-A

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Product name:(9Z,11E)-(S)-13-Trimethylsilanyloxy-octadeca-9,11-dienoic acid methyl ester

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