Total synthesis of halichondrins: Enantioselective construction of a homochiral pentacyclic C1-C15 intermediate from D-ribose

DOI: 10.1016/S0040-4039(00)97476-8

Source and publish data:

Tetrahedron Letters p. 3813 - 3816 (1990)

Update date:2022-08-03

Topics:

Authors:

Cooper, Arthur J.

Salomon, Robert G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)97476-8

The remarkable heterobicyclization of a homochiral acyclic precursor, derived diastereoselectively from D-ribose, is exploited in a synthesis of the intricate multicyclic poly ether C1 to C15 segment of halichondrins.

Full text of DOI:10.1016/S0040-4039(00)97476-8

Products guided by the article

Product name:Benzoic acid (1R,2R)-1-ethoxycarbonyl-2-hydroxy-2-((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-ethyl ester

Cas No:131121-22-7

R&D Labs maybe for 131121-22-7

Richest Group Ltd.

Contact:+86 21 5017 5386

Address:No 999,Jiangyue Rd, Minhang Dist ,201114,Shanghai ,China
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Hangzhou Dingyan Chem Co., Ltd

website:http://www.dingyanchem.com

Contact:86-571-87157530

Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Daqing New Century Fine Chemical Co., Ltd.(expird)

Contact:010-57126694

Address:No.39, jinxing cun, honggang district

Relevant to this article

Models of the reduced forms of polyiron-oxo proteins: An asymmetric, triply carboxylate bridged diiron(II) complex and its reaction with dioxygen

Doi:10.1021/ja00001a023
(1991)
Pd-catalyzed decarboxylative coupling of propiolic acids: One-pot synthesis of 1,4-disubstituted 1,3-diynes via Sonogashira-homocoupling sequence

Doi:10.1021/jo200096x
(2011)
Synthesis of tritium-labelled 3′-azido-3′-deoxythymidine

Doi:10.1002/jlcr.707
(2003)
Optical Isomers of Rocastine and Close Analogues: Synthesis and H1 Antihistaminic Activity of Its Enantiomers and Their Structural Relationship to the Classical Antihistamines

Doi:10.1021/jm00108a012
(1991)
Doi:10.1021/jo01282a042
(1967)
Synthesis of hexasaccharide fragment of lipoarabonomannan from Mycobacteria: Advantages of the benzyl-free approach

Doi:10.1007/s11172-015-0992-5
(2015)

Article Doi