European Journal of Medicinal Chemistry p. 479 - 487 (1990)
Update date:2022-08-05
Topics:
Giordano, C.
Gallina, C.
Consalvi, V.
Scandurra, R.
Epoxidic substrate analogues related to allylamine (4a-4e) and allyl alcohol (5a-5f) were synthesized and tested as models of cysteine-protease inhibitors.They proved to be irreversible inhibitors of papain and cathepsin B with pseudo-first-order inactiva
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