Ionic inhibitors of human leukocyte elastase: Pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide

Article abstract of DOI:10.1002/jps.2600791008

A series of pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide has been synthesized; the compounds have been shown to be highly effective, time-dependent inactivators of human leukocyte elastase. The cationic inhibitor having an