Synthesis of C-(beta-D-glycosyl) analogues of 3-deoxy-D-manno-2-octulosonic acid (Kdo) as potential inhibitors of CMP-Kdo synthetase.

DOI: 10.1016/0008-6215(90)80066-C

Source and publish data:

Carbohydrate research p. 269 - 276 (1990)

Update date:2022-07-29

Topics:

Authors:

Waglund Waglund

Luthman Luthman

Orbe Orbe

Claesson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0008-6215(90)80066-C

Eight C-(beta-D-glycosyl) analogues (14-21) of Kdo (3-deoxy-D-manno-2-octulosonic acid) were obtained from isopropylidene-protected ester precursors and tested in vitro for their inhibitory activity on CMP-Kdo synthetase. None had more than minor inhibitory activity.

Full text of DOI:10.1016/0008-6215(90)80066-C

Products guided by the article

Product name:2,6-anhydro-2-benzyl-3-deoxy-D-glycero-D-talo-octonic acid

Cas No:131389-52-1

R&D Labs maybe for 131389-52-1

Fiarpharmatech Co., Ltd.(expird)

Contact:13482436141

Address:Room 1138, Building 3, No. 555, Huancheng Road(West), Fenxian District, Shanghai
SuZhou Yacoo Science Co., Ltd

website:https://www.yacoo.com.cn/en/

Contact:86-512-87182055

Address:No.112 Xinqing Rd, Suzhou Industrial Park, China, 215125, China
Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China
Qingdao Kingway Pharmtech Co., Ltd.

Contact:86-532-87118899

Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China

Relevant to this article

One-flask synthesis of 1,3,5-trisubstituted 1,2,4-triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition

Doi:10.1039/c4ra00113c
(2014)
Organocatalytic asymmetric Michael-type/wittig reaction of phosphorus ylides: Synthesis of chiral α-methylene-δ-ketoesters

Doi:10.1021/ol201483s
(2011)
Au Nanoparticle-Catalyzed Silaboration of Aryl-Substituted Cyclopropyl Aldehydes Forming Rearranged β-Boronate Silyl Enol Ethers

Doi:10.1002/ejoc.201901408
(2019)
Combined C-H functionalization/cope rearrangement with vinyl ethers as a surrogate for the vinylogous Mukaiyama aldol reaction

Doi:10.1021/ja2051155
(2011)
Compactin from hajos (-)-enedione

Doi:10.1016/S0040-4039(00)97906-1
(1990)
A Convenient Synthesis of Pyranoid Ene Lactones from Phenyl Glycosyl Sulfones

Doi:10.1055/s-1990-27038
(1990)

Article Doi