Tetrahedron Letters p. 5599 - 5602 (1990)
Update date:2022-07-29
Topics: Compactin
Daniewski
Uskokovi
Starting from easily accessible (-)-enedione 8, the hexahydronaphthalene part of compactin 1 was synthesized. The most important steps of this synthesis are: reductive alkylation of 8, cyclization of iodide 12 with SmI2 and Zn, and regiospecifi
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