Addition of α-bromoesters to Azetidine-2,3-diones Promoted by Zinc-Trimethylchlorosilane: A General Synthesis of 3-trimethylsilyloxyazetidin-2-ones and α-Alkylidene β-lactams.

DOI: 10.1016/S0040-4039(00)97082-5

Source and publish data:

Tetrahedron Letters p. 6425 - 6428 (1990)

Update date:2022-08-04

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Authors:

Palomo, Claudio

Aizpurua, Jesus M.

Lopez, M. Concepcion

Aurrekoetxea, Natalia

Oiarbide, Mikel

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Article abstract of DOI:10.1016/S0040-4039(00)97082-5

A convenient procedure for the preparation of α-alkylidene β-lactams from monocyclic azetidine-2,3-diones by means of the Reformatsky reaction is described.

Full text of DOI:10.1016/S0040-4039(00)97082-5

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Product name:[1-(4-Methoxy-phenyl)-2-((E)-1-methyl-2-phenyl-vinyl)-4-oxo-3-trimethylsilanyloxy-azetidin-3-yl]-trimethylsilanyl-acetonitrile

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