The stereochemical outcome from Mitsunobu couplings of vicinal, N-protected acyclic amino alcohols

DOI: 10.1016/S0040-4039(00)98043-2

Source and publish data:

Tetrahedron Letters p. 5253 - 5256 (1990)

Update date:2022-08-02

Topics:

Authors:

Lipshutz

Miller Miller

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)98043-2

Contrary to results expected in Mitsunobu reactions of amides derived from acyclic vic-amino alcohols (i.e., double inversion and hence, retention), urethane derivatives afford products solely of inversion.

Full text of DOI:10.1016/S0040-4039(00)98043-2

Products guided by the article

Product name:Formic acid (1R,2S)-2-(benzyloxycarbonyl-methyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-1-phenyl-propyl ester

Cas No:131751-51-4

R&D Labs maybe for 131751-51-4

Chengda Pharmaceuticals Co., Ltd.

Contact:+86-573-84601188

Address:hengshan Road 5# in Jiashan, zhejiang
AstaTech ( Chengdu) BioPharmaceutical Corp.

website:http://www.astabiochem.cn/

Contact:+86-15198215156-15198215156

Address:SICHUAN CHENGDU
Shanghai Kefu Chemical Co.,Ltd.

Contact:+86-21-34616196

Address:Room601-602, Xuhui Business Building, No.168, Yude Road, Shanghai
Shanghai Korey Pharm Co.,Ltd.(expird)

Contact:021-61840961 021-61840962

Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing

Relevant to this article

Radical-Triggered Tandem Cyclization of 1,6-Enynes with H₂O: A Way to Access Strained 1 H-Cyclopropa[ b]naph thalene-2,7-diones

Doi:10.1021/acs.orglett.8b03007
(2018)
Ladder-type P,S-bridged trans-stilbenes

Doi:10.1021/ic201116p
(2011)
Synthesis and Evaluation of Novel Ether Lipid Nucleoside Conjugates for Anti-HIV-1 Activity

Doi:10.1021/jm00108a025
(1991)
Directing Group Participated Benzylic C(sp³)-H/C(sp²)-H Cross-Dehydrogenative Coupling (CDC): Synthesis of Azapolycycles

Doi:10.1021/acs.orglett.7b03748
(2018)
Fused 1,2,3-dithiazoles: Convenient synthesis, structural characterization, and electrochemical properties

Doi:10.3390/molecules21050596
(2016)
Evaluation of a chiral aryl auxiliary design for sulfur: Construction of auxiliary-modified reagents and stereoselection in sulfoxide formation

Doi:10.1016/S0040-4039(00)97858-4
(1990)

Article Doi