The stereochemical outcome from Mitsunobu couplings of vicinal, N-protected acyclic amino alcohols

DOI: 10.1016/S0040-4039(00)98043-2

Source and publish data:

Tetrahedron Letters p. 5253 - 5256 (1990)

Update date:2022-08-02

Topics:

Authors:

Lipshutz

Miller Miller

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Article abstract of DOI:10.1016/S0040-4039(00)98043-2

Contrary to results expected in Mitsunobu reactions of amides derived from acyclic vic-amino alcohols (i.e., double inversion and hence, retention), urethane derivatives afford products solely of inversion.

Full text of DOI:10.1016/S0040-4039(00)98043-2

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