Synthesis of High Specific Activity (+)- and (-)-6-Fluoronorepinephrine via the Nucleophilic Aromatic Substitution Reaction

DOI: 10.1021/jm00106a043

Source and publish data:

Journal of Medicinal Chemistry p. 767 - 771 (1991)

Update date:2022-08-05

Topics:

Authors:

Ding, Yu-Shin

Fowler, Joanna S.

Gatley, S. John

Dewey, Stephen L.

Wolf, Alfred P.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00106a043

The first example of a no-carrier-added 18F-labeled catecholamine, 6-<18F>fluoronorepinephrine (6-<18F>FNE), has been synthesized via nucleophilic aromatic substitution.The racemic mixture was resolved on a chiral HPLC column to obtain pure samples of (-)

Full text of DOI:10.1021/jm00106a043

Products guided by the article

Product name:(-)-6-<18F>fluoronorepinephrine

Cas No:132128-63-3

R&D Labs maybe for 132128-63-3

Shanghai Massive Chemical Technology Co., Ltd.

website:http://www.massivechem.com/

Contact:+86 21 34943721

Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
NINGBO YINLIANG FOREIGN TRADE CO., LTD.

Contact:+86-574-87834016 / 87898057

Address:23F NO.666JINYU ROAD,YINGZHOU DISTRICT,NINGBO.CHINA
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
TIC Gums, Inc.

Contact:410-273-7300; 800-221-3953

Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA

Relevant to this article

Gold-catalyzed oxidative cyclization of 1,5-enynes using external oxidants

Doi:10.1002/anie.201102581
(2011)
Preparation of potentially bioactive aza and thiaza polycyclic compounds containing a bridgehead nitrogen atom. Synthesis of pyrrolo[1,2,3-de]-1,4-benzothiazine derivatives

Doi:10.1002/jhet.5570270601
(1990)
Total syntheses of (±)-vestitol and bolusanthin III using a wittig strategy

Doi:10.1055/s-0030-1260783
(2011)
Synthesis of (Tetrahydrofuranyl)methyl-1,2,3-triazoles through alkyne-azide cycloaddition catalyzed by a dithioic acid copper(I) complex

Doi:10.1080/00397911.2010.516052
(2011)
Reactions of Carbonyl Compounds in Basic Solutions. Part 12. The Mechanism of the Alkaline Hydrolysis of 3-Substituted Phenyl 2-Acetyl- and 2-Benzoylbenzoates

Doi:10.1039/P29900001805
(1990)
Tertiary Amine-Catalyzed Acyl Group Exchange Reaction of N,O-Diacyl-o-aminophenols. Its Mechanism and Factors Determining the Relative Stability of Acyl Exchanged Isomer Pairs

Doi:10.1246/bcsj.63.3141
(1990)

Article Doi