Preparation of Nε-(3-hydroxy-16-oxoestra-1,3,5(10)-trien-17β-yl)-L-lysine, 16α-hydroxyesterone-lysine adduct, via Heyns rearrangement

DOI: 10.1016/S0040-4039(00)92047-1

Source and publish data:

Tetrahedron Letters p. 1213 - 1214 (1991)

Update date:2022-08-03

Topics:

Authors:

Miyairi Miyairi

Ichikawa

Nambara Nambara

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Article abstract of DOI:10.1016/S0040-4039(00)92047-1

Preparation of a stable covalent adduct from 16α-hydroxyestrone with the ε-amino group of lysine via two step reactions involving Schiff base formation followed by Heyns rearrangement is described.

Full text of DOI:10.1016/S0040-4039(00)92047-1

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