A convenient synthesis of substituted oxazolo-[5,4-b]pyridines using lead tetraacetate as oxidative cyclizing agent

Article abstract of DOI:10.1080/00397919108020814

Various substituted oxazolo[5,4-b]pyridines 5a-d have been synthesized by condensation of appropriate hydroxyaminopyridines and aldehydes followed by oxidative cyclization of the resulting Schiff's bases with lead tetraacetate. This method has been extended to the synthesis of the DNA minor groove binding ligands 5e and 5f related to Hoechst 33258 1.

Full text of DOI:10.1080/00397919108020814

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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A Convenient Synthesis of
Substituted Oxazolo-[5,4-
b]Pyridines Using Lead
Tetraacetate as Oxidative
Cyclizing Agent
Yadagiri Bathini a & J. William Lown a
a Department of Chemistry , University of Alberta
Edmonton , Alberta, Canada , T6G 2G2
Published online: 23 Sep 2006.
To cite this article: Yadagiri Bathini & J. William Lown (1991) A Convenient Synthesis
of Substituted Oxazolo-[5,4-b]Pyridines Using Lead Tetraacetate as Oxidative Cyclizing
Agent, Synthetic Communications: An International Journal for Rapid Communication
of Synthetic Organic Chemistry, 21:2, 215-222, DOI: 10.1080/00397919108020814
To link to this article: http://dx.doi.org/10.1080/00397919108020814
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