A New Vinylsilane Substitution Reaction with Glyoxylate: Asymmetric Synthesis of α-Hydroxy β,γ-Unsaturated Esters

DOI: 10.1021/jo00014a002

Source and publish data:

Journal of Organic Chemistry p. 4337 - 4339 (1991)

Update date:2022-09-26

Topics: Asymmetric synthesis Substitution Reaction Vinylsilane

Authors:

Mikami, Koichi

Wakabayashi, Hideaki

Nakai, Takeshi

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Article abstract of DOI:10.1021/jo00014a002

The vinylsilane substitution reaction with glyoxylate and the asymmetric version thereof are described.These new reactions provide α-hydroxy β,γ-unsaturated esters of biological and synthetic importance in high enantiomeric and geometric purity.

Full text of DOI:10.1021/jo00014a002

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