Copper(i)-catalyzed radical decarboxylative imidation of carboxylic acids with N-fluoroarylsulfonimides

Article abstract of DOI:10.1039/c6cc03227c

An efficient copper-catalyzed radical decarboxylative imidation reaction is presented. This strategy is carried out through the copper(i)-catalyzed decarboxylative C(sp³)-N and C(sp²)-N coupling of carboxylic acids with N-fluoroarylsulfonimides. The reaction shows good functional group tolerance and it provides a new approach for decarboxylative imidation. Preliminary mechanistic studies of this transformation suggest an involvement of N-centered radical species.