Diastereoselective Synthesis of 2,3-anti-5-Benzyloxy-2,4-dimethyl-1,3-pentanediols via Cyclic Hydroboration

Article abstract of DOI:10.1246/bcsj.64.2563

The treatment of (2E,4S)- and (2Z,4S)-1-benzyloxy-5-ethenyloxy-2,4-dimethyl-2-pentene with borane both with and without a catalytic amount of Rh(Ph3P)3Cl gave 2,3-anti-3,4-anti-(2R,3R,4S)- and 2,3-anti-3,4-syn-(2R,3R,4R)-5-benzyloxy-2,4-dimethyl-1,3-penta