Tetrahedron Letters p. 4465 - 4468 (1991)
Update date:2022-08-04
Topics:
Risch
Langhals
Hohberg
The first triple (Grob) fragmentation is described. The process (mechanism) involves retro-Mannich reactions. Easily accessible 1-aza-adamantane derivatives 1 are converted to substituted 5-chloro-resorcinols 5.
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