CAS No.51-35-4,L-Hydroxyproline Suppliers

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Basic Information

Molecular Structure:
CAS No.:	51-35-4
Name:	L-Hydroxyproline
Article Data:	68

Formula:	C₅H₉NO₃
Molecular Weight:	131.131
Synonyms:	Hydroxy-L-proline;(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid;trans-4-Hydroxyproline;L-Proline, 4-hydroxy-, trans-;Hypro;4-Hydroxy-L-proline;trans-4-Hydroxy-L-proline;(2R,4R)-4-hydroxy-2,3,4,5-tetrahydropyrrole-2-carboxylate;(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid;Proline, 4-hydroxy-, L-;
EINECS:	200-091-9
Density:	1.395 g/cm³
Melting Point:	273 °C (dec.)(lit.)
Boiling Point:	355.2 °C at 760 mmHg
Flash Point:	168.6 °C
Solubility:	H₂O: 50 mg/mL
Appearance:	white crystalline powder
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	24/25-36/37/39-27-26
PSA:	69.56000
LogP:	-0.87740

Raw Materials

Downstream Products

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Specification

1. Introduction of L-Hydroxyproline
L-Hydroxyproline, for being one kind of white crystalline powder, has the IUPAC Name of (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid. And it has the Classification Code: Mutation data. Besides, it belongs to the Product Categories which include Nitrogen cyclic compounds; PHARMACEUTICALS; Amino Acids; Pyrrole&Pyrrolidine & Pyrroline; Hydroxyproline [Hyp]; Unusual Amino Acids; Biochemistry; Biological-modified Amino Acids; L-Amino Acids; Amino Acids.

2. Properties of L-Hydroxyproline
L-Hydroxyproline has the following datas: (1)Melting Point: 273 °C (dec.)(lit.); (2)alpha: -75.5 o (c=5, H2O) ; (3)Refractive index: -75.5 °(C=4, H2O) ; (4)Storage temperature: Store at RT. ; (5)Solubility: H2O: 50 mg/mL; (6)Water Solubility: 357.8 g/L (20 °C) ; (7)Index of Refraction: 1.54; (8)Molar Refractivity: 29.49 cm3; (9)Molar Volume: 93.9 cm3; (10)Polarizability: 11.69×10-24 cm3; (11)Surface Tension: 62.2 dyne/cm; (12)Density: 1.395 g/cm3; (13)Flash Point: 168.6 °C; (14)Enthalpy of Vaporization: 69.51 kJ/mol; (15)Boiling Point: 355.2 °C at 760 mmHg; (16)Vapour Pressure: 1.8E-06 mmHg at 25 °C.

3. Structure Descriptors of L-Hydroxyproline
You could convert the following datas into the molecular structure:
(1).InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
(2).InChIKey: InChIKey=PMMYEEVYMWASQN-IMJSIDKUSA-N
(3).Smiles: C1[C@H](NC[C@H]1O)C(=O)O

4. Safety information of L-Hydroxyproline
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36/37/39-27-26
S24/25:Avoid contact with skin and eyes.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S27:Take off immediately all contaminated clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: TW3586500
Hazard Note: Irritant
HazardClass of L-Hydroxyproline: IRRITANT

5. Production of L-Hydroxyproline
L-Hydroxyproline is produced by hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase following protein synthesis (as a post-translational modification). The enzyme catalysed reaction takes place in the lumen of the endoplasmic reticulum.