SYNTHESIS OF POLYHYDROXYLATED INDOLIZIDINE AND QUINOLIZIDINE COMPOUNDS -- POTENT INHIBITORS OF α-GLUCOSIDASE I

DOI: 10.1016/S0040-4039(00)79409-3

Source and publish data:

Tetrahedron Letters p. 5853 - 5856 (1991)

Update date:2022-08-05

Topics:

Authors:

Liu, Paul S.

Rogers, Roland S.

Kang, Mohinder S.

Sunkara, Prasad S.

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Article abstract of DOI:10.1016/S0040-4039(00)79409-3

Polyhydroxylated indolizidine 6a and quinolizidine 6b were synthesized from a common precursor, iminoheptitol 8.The target compounds are potent inhibitors of the glycoprotein trimming enzyme -- α-glucosidase I.

Full text of DOI:10.1016/S0040-4039(00)79409-3

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