Exploiting the divergent reactivity of isocyanoacetates: One-pot three-component synthesis of functionalized angular furoquinolines

DOI: 10.1002/ejoc.201101567

Source and publish data:

European Journal of Organic Chemistry p. 475 - 479 (2012)

Update date:2022-08-05

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Authors:

Bouma, Marinus J.

Masson, Geraldine

Zhu, Jieping

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Article abstract of DOI:10.1002/ejoc.201101567

A one-pot, three-component synthesis of polysubstituted furo[2,3-c]quinoline 1 was developed based on the new reactivity profile of α-(4-nitrophenyl)-α-isocyanoacetates. Simply mixing aldehydes 2, ortho-alkynylanilines 3, and α-(4-nitrophenyl)-α-isocyanoa

Full text of DOI:10.1002/ejoc.201101567

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