Tetrahedron Letters p. 4795 - 4798 (1991)
Update date:2022-08-03
Topics:
Bartholomew
Stocks
Transformation of 3-(chloromethyl)azetidin-2-ones to azetidine-3-carboxylic acid esters is described. The readily available 3-(chloromethyl)azetidin-2-ones rearranged in good yields to azetidine-3-carboxylic acid esters on treatment with alkoxides. An alternative ring opening - ring closure procedure is also identified.
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Doi:10.1021/jo00028a080
(1992)Doi:10.1007/BF00472524
(1991)Doi:10.1055/s-0031-1290602
(2012)Doi:10.1021/ja302808p
(2012)Doi:10.1080/00397910802585860
(2009)Doi:10.1016/j.bmc.2012.03.062
(2012)
