Tetrahedron p. 4320 - 4327 (2012)
Update date:2022-07-30
Topics:
Younai, Ashkaan
Fettinger, James C.
Shaw, Jared T.
The synthesis of γ-lactams from both four-component and imine-anhydride reactions is reported. The synthesis of 2-phenylcyclohexanethiol is described and this compound was evaluated along with an additional seven chiral thiols. A range of selectivity and yields was observed and comparisons to established reactions are made in order to account for the observed reactivity.
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Doi:10.1007/s00044-012-0065-3
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