1377248-64-0Relevant academic research and scientific papers
Influence of chiral thiols on the diastereoselective synthesis of γ-lactams from cyclic anhydrides
Younai, Ashkaan,Fettinger, James C.,Shaw, Jared T.
, p. 4320 - 4327 (2012)
The synthesis of γ-lactams from both four-component and imine-anhydride reactions is reported. The synthesis of 2-phenylcyclohexanethiol is described and this compound was evaluated along with an additional seven chiral thiols. A range of selectivity and yields was observed and comparisons to established reactions are made in order to account for the observed reactivity.
