
Canadian Journal of Chemistry p. 23 - 30 (1994)
Update date:2022-08-03
Topics:
Clark
Jahangir
Langston
Methodology for the preparation of isoquinoline derivatives from N-(tert-butoxycarbonyl)-2-methylbenzylamines (1) was developed. Conversion of 1 to the dilithio species followed by condensation with DMF afforded Boc-3-hydroxy-1,2,3,4-tetrahydroisoquinolin
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