Synthesis of the Staurosporine Aglycon

DOI: 10.1021/jo00033a036

Source and publish data:

Journal of Organic Chemistry p. 2105 - 2114 (1992)

Update date:2022-08-03

Topics:

Authors:

Moody, Christopher J.

Rahimtoola, Kulsum F.

Porter, Barry

Ross, Barry C.

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Article abstract of DOI:10.1021/jo00033a036

A short synthesis of the staurosporine aglycon (6) is reported, the indolocarbazole skeleton being constructed by an intramolecular Diels-Alder reaction followed by a nitrene-mediated ring closure.The synthesis starts by acylation of ethyl indole-2-acetat

Full text of DOI:10.1021/jo00033a036

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Product name:1H-Indole-2-acetic acid, 3-[oxo[(3-phenyl-2-propynyl)amino]acetyl]-, ethyl ester

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