60-00-4

Basic information

• Product Name: EDTA
• Synonyms: Glycine,N,N'-1,2-ethanediylbis[N-(carboxymethyl)-;Aceticacid, (ethylenedinitrilo)tetra- (8CI);3,6-Diazaoctanedioic acid,3,6-bis(carboxymethyl)-;Cheelox;Complexon II;EDTA (chelating agent);Edathamil;Ethylene-N,N'-biscarboxymethyl-N,N'-diglycine;Ethylenediamine-N,N,N',N'-tetraacetic acid;Gluma Cleanser;Havidote;N,N'-1,2-Ethanediyl-bis-N-(carboxymethyl)glycine;Nervanaid B acid;Sequestric acid;Sequestrol;EDTA Acid
• CAS NO: 60-00-4
• Molecular Formula: C₁₀H₁₆N₂O₈
• Molecular Weight: 292.24264
• EINECS: 200-449-4
• Mol File: 60-00-4.mol
• Article Data: 24

Chemical Properties

• Melting Point: 237-245℃ (dec.)
• Boiling Point: 614.2 °C at 760 mmHg
• Flash Point: 325.2 °C
• Appearance: white crystals or powder
• Density: 1.566 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.603
• Water Solubility: 0.5 g/L (25℃)
• CAS DataBase Reference: EDTA(CAS DataBase Reference)
• NIST Chemistry Reference: EDTA(60-00-4)
• EPA Substance Registry System: EDTA(60-00-4)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S26:; S37/39:
• Hazardous Substances Data: 60-00-4(Hazardous Substances Data)

Usage

Chemical Description

Different sources of media describe the Chemical Description of 60-00-4 differently. You can refer to the following data:
1. EDTA is a chelating agent used to sequester metal ions.
2. EDTA is used to stop reactions, PicoGreen is used to detect heteroduplexes, and DMSO is used as a solvent for compounds.
3. EDTA is a chelating agent used to standardize the metal ion solutions.

InChI:InChI=1/C10H16N2O8/c11-9(1-5(13)14,2-6(15)16)10(12,3-7(17)18)4-8(19)20/h1-4,11-12H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

Synthetic route

1,2-dichloro-ethane (107-06-2) + iminodiacetonitrile (628-87-5) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
Stage #1: 1,2-dichloro-ethane; iminodiacetonitrile With calcium oxide In 5,5-dimethyl-1,3-cyclohexadiene at 105 - 115℃; for 9.5h; Large scale; Stage #2: With sodium hydroxide In water at 70 - 80℃; for 9h; Reagent/catalyst; Solvent; Temperature; Large scale;	96.83%

Diethyl iminodiacetate (6290-05-7) + 1,2-dichloro-ethane (107-06-2) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
Stage #1: Diethyl iminodiacetate; 1,2-dichloro-ethane With sodium hydroxide In toluene at 80 - 90℃; for 9.5h; Stage #2: With sodium hydroxide In water at 70 - 80℃; for 4.5h; Reflux;	95.81%

1-Bromo-2-chloroethane (107-04-0) + iminodiacetonitrile (628-87-5) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
Stage #1: 1-Bromo-2-chloroethane; iminodiacetonitrile With calcium oxide In 5,5-dimethyl-1,3-cyclohexadiene at 105 - 115℃; for 9h; Stage #2: With sodium hydroxide In water at 70 - 80℃; for 8.5h;	95.47%

1,2-dichloro-ethane (107-06-2) + iminodiacetic acid (142-73-4) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
Stage #1: 1,2-dichloro-ethane; iminodiacetic acid With sodium hydrogencarbonate In toluene at 80 - 90℃; for 10.5h; Stage #2: With sodium hydroxide In water at 70 - 80℃; for 8.5h; Reflux;	95.29%
With 1,4-dioxane; alkali carbonate at 80 - 125℃;
With alkali carbonate; water at 80 - 125℃;

2,2′-iminobis(acetamide) (21954-96-1) + 1,2-dichloro-ethane (107-06-2) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
Stage #1: 2,2′-iminobis(acetamide); 1,2-dichloro-ethane With calcium hydroxide In toluene at 80 - 90℃; for 11.5h; Stage #2: With sodium hydroxide In water at 70 - 80℃; for 3.5h; Reflux;	95.29%

formaldehyd (50-00-0) + hydrogen cyanide (74-90-8) + ethylenediamine (107-15-3) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With sodium hydroxide

formaldehyd (50-00-0) + sodium cyanide (143-33-9) + ethylenediamine (107-15-3) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With sodium hydroxide at 60℃;

sodium monochloroacetic acid (3926-62-3) + ethylenediamine (107-15-3) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With sodium carbonate at 90 - 95℃;
With sodium carbonate at 90 - 95℃;

furan-2,3,5(4H)-trione pyridine (1:1) + ethylenediamine (107-15-3) + glycolonitrile (107-16-4) → ethylenediaminetetraacetic acid (60-00-4)

ethylene dibromide (106-93-4) + iminodiacetic acid (142-73-4) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With alkali carbonate; water at 80 - 125℃;
With 1,4-dioxane; alkali carbonate at 80 - 125℃;

tetrachloromethane (56-23-5) + formaldehyd (50-00-0) + sodium cyanide (143-33-9) + water (7732-18-5) + ethylenediamine (107-15-3) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
at 10℃;
at 10℃;

1,2-dichloro-ethane (107-06-2) + iminodiacetic acid (142-73-4) + aqueous alkali carbonate → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
at 80 - 120℃;

ethylene dibromide (106-93-4) + iminodiacetic acid (142-73-4) + aqueous alkali carbonate → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
at 80 - 120℃;

ethylenediamine (107-15-3) + sodium amino acetate → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
in wss.-alkal.Loesung vom pH 9.5;

edetate disodium (139-33-3) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With sodium hydroxide In water pH=7.9;
With hydrogenchloride In water
With dihydrogen peroxide; acetic acid In water at 20℃; for 72h;	5.2 mg

tetramethyl ethylenediamine-N,N,N',N'-tetraacetate (19376-45-5) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With water at 90℃; pH=~ 0.5; Product distribution / selectivity;

ethanediyldiimino-tetra-acetic acid tetrapropyl ester (22414-25-1) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With water at 90℃; pH=~ 0.5; Product distribution / selectivity;

ethylenediamine (107-15-3) + glycolonitrile (107-16-4) → ethylenediaminetetraacetic acid (60-00-4)

Conditions	Yield
With water; sodium hydroxide at 12℃; pH=4.06 - 9.82; Temperature; pH-value; Reflux;

manganese(II) perchlorate hexahydrate + ethylenediaminetetraacetic acid (60-00-4) → C20H38Mn3N4O22*4H2O

Conditions	Yield
With sodium hydroxide In water for 0.5h; Reflux;	100%

ethylenediaminetetraacetic acid (60-00-4) → ethylenediaminetetraacetic dianhydride (23911-25-3)

Conditions	Yield
With pyridine; acetic anhydride at 80℃; for 24h;	99%
Stage #1: ethylenediaminetetraacetic acid With pyridine at 65℃; for 1h; Inert atmosphere; Stage #2: With acetic anhydride at 65℃; for 16h;	97%
With pyridine; acetic anhydride at 65℃; for 24h;	94%

ethylenediaminetetraacetic acid (60-00-4) + ethanol (64-17-5) → {[2-(bis-ethoxycarbonylmethyl-amino)-ethyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester (3626-00-4)

Conditions	Yield
Stage #1: ethylenediaminetetraacetic acid; ethanol With sulfuric acid at 90℃; for 17h; Inert atmosphere; Stage #2: With sodium hydrogencarbonate In water pH=9;	98%
With toluene-4-sulfonic acid for 4h; Reflux; Inert atmosphere;	97%
With thionyl chloride at 20℃; for 120h;	80%
With sulfuric acid for 6h; Heating;	70%
With sulfuric acid for 6h; Heating;	70%

bis(triphenylphosphine)palladium(II) dichloride + 2-(2,4-difluorophenyl)-3-(4-iodophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-buten-2-ol (187616-73-5) + ethylenediaminetetraacetic acid (60-00-4) + trimethylsilylacetylene (1066-54-2) → 2-(2,4-difluorophenyl)-3-(4-[trimethylsilylethynyl]phenyl)-1-(1,2,4-triazol-1-yl)-3-buten-2-ol

Conditions	Yield
With copper(I) iodide; triethylamine In water	98%

gallium(III) nitrate + ethylenediaminetetraacetic acid (60-00-4) → (ethylenediaminetetraacetato)aquagallate(III)

Conditions	Yield
With NH3 In water addn. of ammonia to Ga-salt (pptn.), sepn., washing (H2O), mixing with soln. of EDTA, heating with stirring (pH = 1); filtration, crystn. on concn. (evapn., water bath), washing (acetone), drying (90°C); elem. anal.;	98%

morpholine (110-91-8) + gadolinium(III) oxide + ethylenediaminetetraacetic acid (60-00-4) → gadolinium ethylenediamine tetraacetic acid meglumine salt

Conditions	Yield
Stage #1: morpholine; ethylenediaminetetraacetic acid In water for 0.25h; Sonication; Green chemistry; Stage #2: gadolinium(III) oxide In water for 0.333333h; Sonication; Green chemistry;	96%

ethylenediaminetetraacetic acid (60-00-4) + (2R)-2-aminobutan-1-ol (5856-63-3) → (+)-N,N,N',N'-tetrakis{[4-(R)-ethyloxazolin-2-yl]methyl}ethylenediamine (911838-05-6)

Conditions	Yield
Stage #1: ethylenediaminetetraacetic acid; (2R)-2-aminobutan-1-ol In toluene for 20h; Reflux; Stage #2: at 135℃; for 8h;	95%

nickel(II) nitrate hexahydrate + ethylenediaminetetraacetic acid (60-00-4) + N,N-dimethyl-formamide (68-12-2, 33513-42-7) → Ni2EDTA*1.5DMF*5H2O

Conditions	Yield
With triethylamine	95%

ethylenediaminetetraacetic acid (60-00-4) + acetic anhydride (108-24-7) → C12H16N2O4

Conditions	Yield
With potassium acetate In dimethyl sulfoxide at 55℃; for 1.5h;	94.58%

ethylenediaminetetraacetic acid (60-00-4) + cobalt(II) carbonate (759403-02-6) → d,l-Ba{Coaedt}2*4H2O

Conditions	Yield
With dihydrogen peroxide In water byproducts: H2{Coaedtaq}*2H2O; heating of a suspension of CoCO3 and C10H16N2O8 in H2O under vivious stirring slowly to 75°C; oxidation with 30% aq. H2O2-soln. under pptn. of H2(Coaedtaq)*2H2O; addn. of BaCO3-powder; filtration; slow pouring of the filtrate in ethanol;; washing with ethanol for two times; drying for 24 h at 50°C;;	94%
With H2O2 In water byproducts: H2{Coaedtaq}*2H2O; heating of a suspension of CoCO3 and C10H16N2O8 in H2O under vivious stirring slowly to 75°C; oxidation with 30% aq. H2O2-soln. under pptn. of H2(Coaedtaq)*2H2O; addn. of BaCO3-powder; filtration; slow pouring of the filtrate in ethanol;; washing with ethanol for two times; drying for 24 h at 50°C;;	94%

cobalt(II) nitrate hexahydrate + ethylenediaminetetraacetic acid (60-00-4) → (ethylenediaminetetraacetato)cobalt(II)(2-) (110169-73-8, 110169-72-7, 14931-83-0)

Conditions	Yield
In water for 0.5h;	91.1%

ethylenediaminetetraacetic acid (60-00-4) + acetic anhydride (108-24-7) → ethylenediaminetetraacetic dianhydride (23911-25-3)

Conditions	Yield
In pyridine at 65℃; for 24h; Inert atmosphere;	91%
With triethylamine In dimethyl sulfoxide at 55℃; for 1.5h; Reagent/catalyst; Reflux;	75.17%

ethylenediaminetetraacetic acid (60-00-4) + vanadium(III) chloride (7718-98-1) → potassium (ethylenediamine-N,N,N',N'-tetraacetato)aquavanadate(III)*2H2O

Conditions	Yield
With K2CO3 In water Under inert atmosphere, neutralizing of H4edta soln. with K2CO3, addn. of VCl3 to the soln., stirring (15 min).; Evapn. of solvent, addn. of EtOH gives pale brown crystals, filtn., washing (EtOH, ether), elem. anal.;	90%

malachite + ethylenediaminetetraacetic acid (60-00-4) + water (7732-18-5) + adenine (66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9) → (diadeninium [(ethylenediamine-N,N,N',N'-tetraacetato)copper]) hydrate

Conditions	Yield
In water byproducts: CO2; Cu:H4EDTA:adenine=1:1:2 molar ratio, Cu compd. and H4EDTA heated (15 min, <50°C, vac.) in water, stirred with heating at 60° for 30 min, cooled to room temp., slowly filtered, adenine added, stirred; filtered, slow evapd. at room temp. (1-2 wk), ppt. filtered, washed (cold water), air-dried; elem. anal.;	90%

malachite + ethylenediaminetetraacetic acid (60-00-4) + water (7732-18-5) + adenine (66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9) → (adeninium [aqua(ethylenediamine-N,N,N'-triacetato-N'-acetic acid)copper]) dihydrate

Conditions	Yield
In water byproducts: CO2; Cu compd. and H4EDTA heated (15 min, <50°C, vac.) in water, stirred with heating at 60° for 30 min, cooled to room temp., slowly filtered, adenine added, stirred; filtered, slow evapd. at room temp. (1-2 wk), crysts. filtered, washed (cold water), air-dried; elem. anal.;	90%

neodymium(III) nitrate hydrate + ethylenediaminetetraacetic acid (60-00-4) + hydrazine hydrate (7803-57-8) → hydrazinium ethylenediaminetetraacetatotriaquoneodymium pentahydrate

Conditions	Yield
In water byproducts: HNO3, H2O; aq. soln. of tetraacetatic acid (1 equiv.) and hydrazine hydrate (4 equiv.) was added to aq. soln. of nitrate; filtered; kept at room temp. for 2-3 d; filtered; quickly washed (cold H2O, EtOH); dried in air; elem. anal.;	90%

samarium(III) nitrate hydrate + ethylenediaminetetraacetic acid (60-00-4) + hydrazine hydrate (7803-57-8) → hydrazinium ethylenediaminetetraacetatotriaquosamarium pentahydrate

Conditions	Yield
In water byproducts: HNO3, H2O; aq. soln. of tetraacetatic acid (1 equiv.) and hydrazine hydrate (4 equiv.) was added to aq. soln. of nitrate; filtered; kept at room temp. for 2-3 d; filtered; quickly washed (cold H2O, EtOH); dried in air; elem. anal.;	90%

dysprosium(III) nitrate hydrate + ethylenediaminetetraacetic acid (60-00-4) + water (7732-18-5) + hydrazine hydrate (7803-57-8) → hydrazinium dysprosium(III) ethylenediaminetetraacetate hydrate

Conditions	Yield
In water addn. aq. soln. of ethylenediaminetetraacetic acid (0.01 mol) and N2H4*H2O (0.04 mol) to aq. soln. of Dy(NO3)3*nH2O with stirring; kept at atm. pressure at room temp. for 30 min; filtered; allowed to stand at room temp. for 8-9 w for crystn.; crystalsfiltered off, washed (several times ice-cold distd. H2O), air-dried; el em. anal.;	90%

terbium(III) nitrate hydrate + ethylenediaminetetraacetic acid (60-00-4) + water (7732-18-5) + hydrazine hydrate (7803-57-8) → hydrazinium terbium(III) ethylenediaminetetraacetate hydrate

Conditions	Yield
In water addn. aq. soln. of ethylenediaminetetraacetic acid (0.01 mol) and N2H4*H2O (0.04 mol) to aq. soln. of Tb(NO3)3*nH2O with stirring; kept at atm. pressure at room temp. for 30 min; filtered; allowed to stand at room temp. for 8-9 w for crystn.; crystalsfiltered off, washed (several times ice-cold distd. H2O), air-dried; el em. anal.;	90%

cobalt(II) chloride hexahydrate + ethylenediaminetetraacetic acid (60-00-4) + sodium hydroxide (1310-73-2) → Na2n[Co(ethylenediaminetetraacetate)]n·4nH2O

Conditions	Yield
at 20℃; for 1h; pH=3;	88.1%

iron(III) chloride + ethylenediaminetetraacetic acid (60-00-4) + sodium hydrogencarbonate (144-55-8) → ethylenediaminetetraacetic acid ferric sodium salt

Conditions	Yield
In water at 90℃; for 1h; pH=7; Large scale;	88.1%

ethylenediaminetetraacetic acid (60-00-4) + RuO2*(3-4)H2O → 3H(1+)*Ru(3+)*2Cl(1-)*(CH2N(CH2COO)2)2(4-)*3.5H2O=H[RuCl2(CH2N(CH2COO)(CH2COOH))2]*3.5H2O

Conditions	Yield
With HCl In water RuO2*(3-4)H2O dissolved in concd. HCl by heating, evapd. to dryness, residue dissolved in H2O, org. compd. added, mixture heated until clear soln. appeared, soln. heated at 120°C for 5 h; cooling, washing (EtOH, acetone); elem. anal.;	85%

gadolinium nitrate hydrate + ethylenediaminetetraacetic acid (60-00-4) + water (7732-18-5) + hydrazine hydrate (7803-57-8) → hydrazinium gadolinium(III) ethylenediaminetetraacetate hydrate

Conditions	Yield
In water addn. aq. soln. of ethylenediaminetetraacetic acid (0.01 mol) and N2H4*H2O (0.04 mol) to aq. soln. of Gd(NO3)3*nH2O with stirring; kept at atm. pressure at room temp. for 30 min; filtered; allowed to stand at room temp. for 8-9 w for crystn.; crystalsfiltered off, washed (several times ice-cold distd. H2O), air-dried; el em. anal.; TGA;	85%

uranyl nirate hexahydrate + ethylenediaminetetraacetic acid (60-00-4) → (ethylenediamine-NNN'N'-tetra-acetic acid)dioxoperoxouranium(VI)

Conditions	Yield
With ammonium hydroxide; sulfuric acid; dihydrogen peroxide In sulfuric acid; water Addn. of aq. ammonia to an aq. soln. of U-compound until a yellow ppt. ceases to appear, filtn., washing, treating with aq. H2SO4, filtn., cooling (ice-bath), addn. of H4edta with stirring, addn. of an excess of H2O2.; Filtn., washing (EtOH), drying in vac. over conc. H2SO4, elem. anal.;	84%

gadolinium(III) oxide + ethylenediaminetetraacetic acid (60-00-4) + 1-deoxy-1-(methylamino)-D-glucitol (6284-40-8) → gadolinium ethylenediamine tetraacetic acid meglumine salt (85993-65-3)

Conditions	Yield
Stage #1: ethylenediaminetetraacetic acid; 1-deoxy-1-(methylamino)-D-glucitol In water for 0.25h; Sonication; Green chemistry; Stage #2: gadolinium(III) oxide In water for 0.333333h; Sonication; Green chemistry;	84%

Upstream product

• 107-15-3 ethylenediamine 
• 107-16-4 glycolonitrile 
• 106-93-4 ethylene dibromide 
• 142-73-4 iminodiacetic acid 
• 56-23-5 tetrachloromethane 
• 50-00-0 formaldehyd 
• 143-33-9 sodium cyanide 
• 7732-18-5 water 
• 107-06-2 1,2-dichloro-ethane 
• 21954-96-1 2,2′-iminobis(acetamide) 
• 107-04-0 1-Bromo-2-chloroethane 
• 628-87-5 iminodiacetonitrile 
• 6290-05-7 Diethyl iminodiacetate 
• 139-33-3 edetate disodium 

Downstream Products

• 119531-02-1 N,N,N',N'-Tetrakis(cyclohexyl acetate)ethylenediamine 
• 128660-11-7 {[2-(Bis-cyclohexyloxycarbonylmethyl-amino)-ethyl]-cyclohexyloxycarbonylmethyl-amino}-acetic acid 
• 302-01-2 hydrazine 
• 3626-00-4 ethylenediaminetetraacetic acid tetraethyl ester 
• 126216-32-8 N-<2-ethyl>-N-(carboxymethyl)-DL-phenylalanine Tetramethyl Ester 
• 126216-35-1 N-<2-ethyl>-N-(carboxymethyl)-4-amino-DL-phenylalanine Tetramethyl Ester 
• 126216-33-9 N-<2-ethyl>-N-(carboxymethyl)-4-nitro-DL-phenylalanine Tetramethyl Ester 
• 126216-37-3 N-<2-ethyl>-N-(carboxymethyl)-4-amino-DL-phenylalanine Tetralithium Salt 
• 126216-38-4 N-<2-ethyl>-N-(carboxymethyl)-4-isothiocyanato-DL-phenylalanine Dilithium Salt 
• 446-32-2 4-fluoroanthranilic acid 
• 77439-55-5 6'-hydroxy-2-<2-methoxy-4-(methylsulfinyl)phenyl>-1H-imidazo<4,5-b>pyridine 
• 853-27-0 3,20-dioxo-4-pregnen-21-al 
• 76150-45-3 Cu⁽²⁺⁾*C₁₀H₁₄N₂O₈^(2-)*SC(S)N(C₆H₄OH)C(O)CH₂=Cu(C₁₀H₁₄N₂O₈)(SC(S)N(C₆H₄OH)C(O)CH₂) 
• 110169-73-8 (ethylenediaminetetraacetato)cobalt(II)^(2-) 

Relevant articles and documents

-

-

A high and constant hydration of the nuclear magnetic resonance imaging contrast agent and its preparation method

The invention relates to a nuclear magnetic resonance imaging contrast agent with a high hydration constant and a preparation method of the nuclear magnetic resonance imaging contrast agent. The nuclear magnetic resonance imaging contrast agent with the high hydration constant is a gadolinium (III) complex containing nitrogen oxygen groups. The nuclear magnetic resonance imaging contrast agent prepared by the gadolinium (III) complex has the advantages of high hydration constant, relatively good stability and high relaxation rate.

Synthesis and Characterization of CeO2 Nanoparticles via Solution Combustion Method for Photocatalytic and Antibacterial Activity Studies

CeO2 nanoparticles have been proven to be competent photocatalysts for environmental applications because of their strong redox ability, nontoxicity, long-term stability, and low cost. We have synthesized CeO2 nanoparticles via solution combustion method using ceric ammonium nitrate as an oxidizer and ethylenediaminetetraacetic acid (EDTA) as fuel at 450°C. These nanoparticles exhibit good photocatalytic degradation and antibacterial activity. The obtained product was characterized by various techniques. X-ray diffraction data confirms a cerianite structure: a cubic phase CeO2 having crystallite size of 35 nm. The infrared spectrum shows a strong band below 700 cm-1 due to the Ce-O-Ce stretching vibrations. The UV/Vis spectrum shows maximum absorption at 302 nm. The photoluminescence spectrum shows characteristic peaks of CeO2 nanoparticles. Scanning electron microscopy (SEM) images clearly show the presence of a porous network with a lot of voids. From transmission electron microscopy (TEM) images, it is clear that the particles are almost spherical, and the average size of the nanoparticles is found to be 42 nm. CeO2 nanoparticles exhibit photocatalytic activity against trypan blue at pH 10 in UV light, and the reaction follows pseudo first-order kinetics. Finally, CeO2 nanoparticles also reduce CrVI to CrIII and show antibacterial activity against Pseudomonas aeruginosa.