A Facile Sythesis of 1,2,3,4-Tetrahydroisoquinolines Through Cyclization of O,N-Acetals

DOI: 10.1055/s-1987-28089

Source and publish data:

Synthesis p. 824 - 827 (1987)

Update date:2022-09-26

Topics:

Authors:

Kubo, Akinori

Saito, Naoki

Kawakami, Nanko

Matsuyama, Yasuo

Miwa, Teruyo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1987-28089

A mild and efficient method for the synthesis of 1,2,3,4-tetrahydroisoquinolines by a modified Pictet-Spengler reaction involving Lewis acid-mediated cyclization of O,N-acetals is described.

Full text of DOI:10.1055/s-1987-28089

Products guided by the article

Product name:Benzene, 1,3-dimethoxy-2-methyl-4-(2-nitroethenyl)-, (E)-

Cas No:139122-89-7

R&D Labs maybe for 139122-89-7

Changzhou Sunlight Pharmaceutical Co., Ltd.

Contact:+86-519-83131668;83139028;83138042;83137041

Address:JiuliStreet, Benniu Town Changzhou City, Jiangsu Province
Hangzhou GreenCo Science & Technology Co., Ltd.

Contact:86-571-88257303

Address:1713 Room,Jingui Building,Gudun Road,Xihu District,Hangzhou,China
jintan yufan Medicine Raw materials Co.,Ltd.(expird)

Contact:86-519-82808282

Address:6th,Jincheng Huangzhuang
ABA Chemicals (Shanghai) Limited

Contact:021- 5115 9199-232

Address:Suite 18D, #201 Ningxia Road,
Beijing Cooperate Pharmaceutical Co.,Ltd

website:http://www.cooperate-pharm.com/

Contact:86-01060279497

Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base

Relevant to this article

"Bicyclobenzodiazepinones" from 3-oxo-1,2-diazetidinium hydroxide, inner salts

Doi:10.1016/S0040-4020(01)91027-0
(1991)
Metaproterenol, isoproterenol, and their bisdimethylcarbamate derivatives as human cholinesterase inhibitors

Doi:10.1021/jm300289k
(2012)
Synthesis and self-assembly processes of monofunctionalized Cucurbit[7]uril

Doi:10.1021/ja3058502
(2012)
Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: Towards the development of potential dual action antimalarials

Doi:10.1016/j.ejmech.2012.05.022
(2012)
Synthesis and evaluation of 2,4,6-trisubstituted pyrimidine derivatives as novel antileishmanial agents

Doi:10.1007/s00044-012-0167-y
(2013)
An efficient synthesis of the precursors of [¹¹C]MDL 100907 labeled in two specific positions

Doi:10.1002/(SICI)1099-1344(199910)42:10<949::AID-JLCR253>3.0.CO;2-S
(1999)

Article Doi