Tetrahedron Letters p. 7283 - 7286 (1992)
Update date:2022-08-05
Topics:
Flynn, Daniel L.
Becker, Daniel P.
Nosal, Roger
Zabrowski, Daniel L.
A route to azanoradamantanes is described which makes use of an atom-transfer radical cyclization to afford 3-azabicyclo<3.3.0>ocatanes 3A and 3B.Subsequent elaboration of exo-allylamine functionality, followed by cyclization of the endo-hydroxymethyl intermediate 9, affords the new azanoradamantanes 11 and 4.This new azatricyclic system is useful for producing serotonin 5-HT3 antagonists and 5-HT4 agonists. Key words: Azanoradamantane; 3-azabicyclo<3.3.0>octane; serotonin
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Doi:10.1002/chem.201200821
(2012)Doi:10.1007/s00044-013-0523-6
(2013)Doi:10.1016/0040-4039(91)80116-N
(1991)Doi:10.1016/S0957-4166(00)80018-X
(1991)Doi:10.1023/A:1024468813689
(2003)Doi:10.1039/c2cc34060g
(2012)
