Preparation of Functionalized Dialkylzinc Reagents via an Iodine-Zinc Exchange Reaction. Highly Enantioselective Synthesis of Functionalized Secondary Alcohols

DOI: 10.1021/jo00033a008

Source and publish data:

Journal of Organic Chemistry p. 1956 - 1958 (1992)

Update date:2022-08-05

Topics: Enantioselective synthesis

Authors:

Rozema, Michael J.

AchyuthaRao, Sidduri

Knochel, Paul

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00033a008

Functionalized dialkylzincs are obtained by the reaction of polyfunctional alkyl iodides with Et2Zn in excellent yield.Their treatment with aldehydes, in the presence of the titanium catalyst 6, affords functionalized secondary alcohols with high enantios

Full text of DOI:10.1021/jo00033a008

Products guided by the article

Product name:9-Oxo-7-phenyl-decanenitrile

Cas No:139527-09-6

R&D Labs maybe for 139527-09-6

Sarchem Laboratories, Inc.

Contact:732.938.2777

Address:5012 Industrial Road Farmingdale, NJ 07727
chengdu firsterchem Pharmaceutical Co., Ltd.

Contact:028-66825849

Address:chengdu
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Hangzhou utanpharma Co., Ltd

Contact:86-571-87758773

Address:Room604 ,6F, Block A1-3 Xixi Plaza,No. 588 Wenyi West RD, Hangzhou,310012, China
Xinyanhe Pharmatech Co.,Ltd

Contact:+86-519-8525-2752

Address:Changzhou

Relevant to this article

Palladium-catalysed Coupling of Trialkylstannyltetrathiafulvalenes with Aryl Halides

Doi:10.1039/c39920000158
(1992)
Tailor-made synthesis of various backbone-substituted imidazolinium salts by triflic anhydride mediated intramolecular cyclisation

Doi:10.1039/c2cc34952c
(2012)
A Facile and efficient procedure for the synthesis of new benzimidazole-2-thione derivatives

Doi:10.3390/molecules17078578
(2012)
Asymmetric Carbonyl Addition Reactions to Benzyloxyaldehydes by Binaphthol-Titanium Catalyst: Anti- vs. Syn-Diastereofacial Preference in Anomalous Nonchelation Complexation

Doi:10.1016/S0040-4039(97)00231-1
(1997)
Doi:10.1039/j39690001556
(1969)
Reaction between 4-Nitro-1,3-diarylbutan-1-ones and Ammonium Acetate in the Presence of Morpholine and Sulfur: An Efficient Synthesis of 2,4-Diarylpyrroles

Doi:10.1055/s-0035-1561852
(2016)

Article Doi