Preparation of Functionalized Dialkylzinc Reagents via an Iodine-Zinc Exchange Reaction. Highly Enantioselective Synthesis of Functionalized Secondary Alcohols

DOI: 10.1021/jo00033a008

Source and publish data:

Journal of Organic Chemistry p. 1956 - 1958 (1992)

Update date:2022-08-05

Topics: Enantioselective synthesis

Authors:

Rozema, Michael J.

AchyuthaRao, Sidduri

Knochel, Paul

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00033a008

Functionalized dialkylzincs are obtained by the reaction of polyfunctional alkyl iodides with Et2Zn in excellent yield.Their treatment with aldehydes, in the presence of the titanium catalyst 6, affords functionalized secondary alcohols with high enantios

Full text of DOI:10.1021/jo00033a008

Products guided by the article

Product name:9-Oxo-7-phenyl-decanenitrile

Cas No:139527-09-6

R&D Labs maybe for 139527-09-6

Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
ShangHai Ruiyi Medical Technology Co.,Ltd.

Contact:+86-21-54718086

Address:No951 Jianchuan RD，Minhang District
Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
puyang hongda shengdao new material co.,ltd.

Contact:+86-393- 4896278

Address:No.29 East Zhongyuan Road
Shanghai Norky Pharmaceutical Co., LTD.

website:http://www.norkypharm.com

Contact:86-21-61075300

Address:1165 Jiangning Road, Office 1502, Shanghai, China

Relevant to this article

Palladium-catalysed Coupling of Trialkylstannyltetrathiafulvalenes with Aryl Halides

Doi:10.1039/c39920000158
(1992)
Tailor-made synthesis of various backbone-substituted imidazolinium salts by triflic anhydride mediated intramolecular cyclisation

Doi:10.1039/c2cc34952c
(2012)
A Facile and efficient procedure for the synthesis of new benzimidazole-2-thione derivatives

Doi:10.3390/molecules17078578
(2012)
Asymmetric Carbonyl Addition Reactions to Benzyloxyaldehydes by Binaphthol-Titanium Catalyst: Anti- vs. Syn-Diastereofacial Preference in Anomalous Nonchelation Complexation

Doi:10.1016/S0040-4039(97)00231-1
(1997)
Doi:10.1039/j39690001556
(1969)
Reaction between 4-Nitro-1,3-diarylbutan-1-ones and Ammonium Acetate in the Presence of Morpholine and Sulfur: An Efficient Synthesis of 2,4-Diarylpyrroles

Doi:10.1055/s-0035-1561852
(2016)

Article Doi