Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship

DOI: 10.1016/j.ejmech.2013.01.030

Source and publish data:

European Journal of Medicinal Chemistry p. 597 - 604 (2013)

Update date:2022-08-04

Topics:

Authors:

Gao, Rui

Liao, Sha

Zhang, Chen

Zhu, Weilong

Wang, Liyan

Huang, Jin

Zhao, Zhenjiang

Li, Honglin

Qian, Xuhong

Xu, Yufang

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Article abstract of DOI:10.1016/j.ejmech.2013.01.030

In this study, starting from a lead compound discovered by virtual screening, a series of novel heterocyclic substituted benzenesulfonamides were designed and synthesized as new carbonic anhydrase IX (CA IX) inhibitors. Some compounds exhibited potent inh

Full text of DOI:10.1016/j.ejmech.2013.01.030

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Product name:4-((4-bromophthalazin-1-yl)amino)benzenesulfonamide

Cas No:1402423-55-5

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