Chemical and Pharmaceutical Bulletin p. 666 - 674 (1992)
Update date:2022-09-26
Topics:
Yamanaka
Suda
Yoneda
Ohhara
The metabolite of loprinone (E-1020) in dogs, 5-(2-aminopyridin-5-yl)-1,2-dihydro-6-methyl-2-oxo-3-pyridine carbonitrile (9), was prepared via ozonolysis of imidazo[1,2-a]pyridinylpyridines and evaluated for positive inotropic activity. Its potency was le
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