On the reaction of sterically hindered α,β-unsaturated ketones with hydroxylamine: Preparation of 5-hydroxy derivatives of isoxazolidine and 4,5-dihydroisoxazole

Article abstract of DOI:10.1007/s11172-012-0088-4

A reaction of hydroxylamine with α,β-unsaturated ketones containing a tertiary carbon atom α to the keto group leads to 5-hydroxyisoxazolidine and 5-hydroxy-Δ²-isoxazoline derivatives.